Bacopa Monnieri Benefits Those with Anxiety

Bacopa Monnieri
Bacopa Monnieri is a flowering plant.

Bacopa Monnieri is a nootropic herb that is known for its benefits as an anxiolytic.  It is highly ranked in Ayurvedic remedies, and is incredibly powerful when it comes to combating anxiety.

 

Bacopa Monnieri extract has even been shown to work better than traditional approaches to reducing anxiety because it increases cognition and alertness rather than reducing it [1].  Bacopa benefits people across a wide age range, and has been shown to increase memory as well as improve mood.

How Does Bacopa Monnieri Work?

 

The anti-anxiety effects of Bacopa are still being researched, but can be attributed to a combination of saponins in the herb and its ability to increase serotonin.  Saponins are chemical compounds that are part of a plant’s immune system.  When they are consumed by humans, they can have effects like anxiety reduction and improved mood [2].  The supplement helps to improve neural communication by helping nerve cells send out signals.  Basically, it helps your brain to have better control over its reactions, which helps to manage stress and anxiety faster.

 

Because Bacopa also causes an increase in serotonin production, it results in a surge of “feel-good” hormones that aid in anxiety reduction.  Bacopa Monnieri is a great option as an anxiolytic nootropic, and a powerful one at that, because it affects the mental condition and can improve not only mood, but memory and performance as well.

Bacopa Monnieri Benefits

 

Finding the correct Bacopa Monnieri dosage benefits those suffering from anxiety
This supplement can help relieve anxiety.

While Bacopa Monnieri is powerful as an anxiolytic, it truly is most effective because it is neither a stimulant nor a depressant.  While other supplements for anxiety may cause drowsiness or overstimulation, Bacopa does neither of these.

 

It will improve cognitive function rather than impairing it for the sake of reducing stress.  While Bacopa can act as a mental sedative, it won’t cause tiredness and will instead focus the mind.

 

Bacopa Monnieri is also an antioxidant, protecting cells from damage and preventing their breakdown.  This is just an added perk to the supplement that can effectively reduce anxiety without causing other negative mental side effects.

Bacopa Monnieri Dosage

 

Dosage will largely depend on the extract of Bacosides. For example, a formulation of 20% Bacosides will call for 750mg once per day. Dosage will also depend on the individual’s levels of stress an anxiety.  The supplement can be taken at any time since it won’t cause drowsiness or overstimulation meaning it won’t interfere with your sleep cycle.

The Bacopa supplement is best taken with food, and can be easily worked into a daily routine by having it with a meal.  In a very short time, adding this supplement every day can help reduce anxiety as well as provide more mental focus and an improved memory.

Sources

 

  1. http://www.ncbi.nlm.nih.gov/pubmed/23195757
  2. http://phoenixhealth.me/Botanical%20medicine/Bacopa%20for%20the%20Brain.pdf

Using St. John’s Wort to Boost Mood

st. john's wort
St. John’s Wort is a yellow flowering plant.

Depression affects 121 Million people worldwide. In its severe forms, it leads to 850,000 deaths each year. [1]

There are many kinds of medication that can be prescribed by doctors to treat this condition. St. John’s Wort, on the other hand, is an herbal remedy avialable over the counter for mood.

What is St.John’s Wort?

St. John’s Wort belongs to the plant species Hypericum perforatum, and is also known as Tipton’s weed, rosin rose, goatweed, chase-devil, or Klamath weed. There are many species worldwide and they can mostly be found in North America, Europe, Turkey, Middle East, India, China and Brazil. [2] Australia is the world’s top producer of the plant.

Its name was given because it blooms around June 24, the birthday of John the Baptist. “Wort” is an old English word for plant. It is used for multiple problems such as for chronic fatigue syndrome, exhaustion, migraines, and muscle pain. An oil extract from the plant can also be used for easing scrapes, bruises and other inflammations. [3]

How does it Work?

What If I Can’t Take SJW?

Some individuals cannot take St. John’s Wort, such as those who take contraceptive pills. It also interacts negatively with a variety of other medications, so be sure to discuss it with your doctor first. Some alternative anxioltyic supplements include:

  1. Rhodiola Rosea Supplement
  2. Ashwagandha Powder
  3. Theanine Supplement

Scientists do not yet fully understand how St. John’s Wort works in relation to mood. Its effect is generally attributed to its content of hypericin, hyperflorin, and flavonoids which help elevate dopamine, norepinephrine, and serotonin. [4]

Dopamine is a stimulant that produces good mood. In elevated levels, it makes the user more focused, confident and interested in what he’s are doing. Norepinephrine is similar to dopamine and produces alertness and motivation. Serotonin on the other hand manages mood, appetite, and sleep. With low levels of Serotonin, one will become anxious, irritable, and have trouble sleeping. [5]

During a six week trial involving patients with mood issues, a hypericum extract of 300 mg or 600 mg was given to one group while the other group used Paroxetine in 20 mg capsules. After six weeks, it was discovered that hypericum extract is as effective as paroxetine for patients with moderate or severe mood issues.[7]

Dosage

hypericum
St. John’s Wort is also known as Hypericum.

St. John’s Wort is available in both liquid and pill form. For regular use, a dose of 300 mg taken 3 times a day with meals. [8] The effects of the supplement may be seen in 3-4 weeks and it is recommended that you don’t stop taking it before that. [6]

Sources

1. http://www.sciencedaily.com/releases/2011/07/110725202240.htm
2. https://en.wikipedia.org/wiki/St_John’s_wort
3. http://www.nlm.nih.gov/medlineplus/druginfo/natural/329.html
4. http://health.howstuffworks.com/wellness/natural-medicine/herbal-remedies/question468.htm
5. http://thedea.org/yourbrain.html
6. http://umm.edu/health/medical/altmed/herb/st-johns-wort
7. http://www.bmj.com/content/330/7490/503
8. http://www.webmd.com/depression/guide/st-johns-wort

Ashwagandha Rhodiola and other Anxiety Relief Supplements

What Is Anxiety?

Many supplements including Rhodiola are great for anxiety relief
Anxiety can affect you in many ways

Anxiety is a normal reaction to stress and at times can prove beneficial. Unfortunately, there are people who experience an excess of this response, and no matter how unnecessary they may understand the anxiety to be, there is nothing they can do about it because it is not something that can be controlled logically.

From PTSD (post-traumatic stress disorder) to social anxiety, all the way on to OCD (obsessive-compulsive disorder), disorders featuring anxiety are the most common mental issues experienced by Americans.
Continue reading “Ashwagandha Rhodiola and other Anxiety Relief Supplements”

How the Male and Female Brains Differ in Stress Response

stress and the body's responseResearch published by the University of Pennsylvania (UPenn) suggests that men and women deal with stress in different ways. Because of this difference in coping, men and women can experience different health issues as a result of stress. These health issues can pose a real threat, and thus it is important to minimize stressors. However, in a society focused on end results and productivity, avoiding stressors is not likely. Fortunately, there are natural ways to help manage the strain.

UPenn researchers state that “In men, it was found that stress was associated with increased CBF in the right prefrontal cortex and CBF reduction in the left orbitofrontal cortex. In women, the limbic system – a part of the brain primarily involved in emotion – was activated when they were under stress.” Fancy talk, right? What the researchers found is that Continue reading “How the Male and Female Brains Differ in Stress Response”

Picamilon VS Phenibut: Dosage Benefits and Side Effects Reviewed

Finding the correct phenibut dosage is key for anxiety relief

Stress is a part of everyday life.  It can fuel productivity and in many ways is a natural part of the world.  However, sometimes stress can become overwhelming and hard to deal with.  After a long day at school or work, it isn’t always possible to relax what with worries about what the next day will bring.

Luckily, for those of us who experience excessive stress, there are a few supplements that may be able to help.  Read on to learn more about Picamilon’s and Phenibut’s stress relieving properties.

Phenibut Review

Phenibut is a derivative of the neurotransmitter GABA. It is able to cross the blood-brain barrier and as a result is fast acting. GABA is the primary inhibitory chemical within the brain and is noted for having both anti-anxiety and nootropic properties.

One of the main benefits and chief uses of Phenibut powder is to help reduce anxiety. When combined with other Nootropic supplements, this effect can be amplified.

There is also some evidence that Phenibut may help to protect neurons from low oxygen levels and even help to stimulate the neurotransmitter Acetylcholine.

Speaking of these Nootropic benefits, it appears that Phenibut may also result in increased attention, focus, and concentration. Phenibut is also helpful against insomnia, although some evidence suggests that this effect will wear off as a tolerance begins to build so this is a supplement that should be cycled. Most users take phenibut for three days then cycle off for two days; others simply take it every four days. This ensures that there is no tolerance build up and you can avoid any withdrawl.

Picamilon Review

Picamilon is known as a prodrug of GABA and used for a number of the same reasons as Phenibut. However, Phenibut’s mechanism of action is slightly different. What happens is that as Phenibut crosses the blood-brain barrier, the supplement splits into GABA and niacin as a result of hydrolysis.

This leads to a decrease in anxiety (due to the GABA) and also a powerful vasodilation effect. The niacin is able to widen the blood vessels by relaxing the smooth muscle cells in arteries and larger veins. As you might expect, the anti-anxiety effect is rather significant. However, this supplement also enhances learning and memory and is probably a bit more effective than Phenibut for this purpose.

Picamilon dosage also seems to directly correlate to specific benefits. For example, when taking 50mg three times a day, most of the effects are relaxing and anti-anxiety related. However, when this is increased to 100mg three times a day, nutritional stimulation and increased endurance occur, which is excellent news for bodybuilders and weight lifters.

Picamilon Dosage

When cycling any supplement into your diet, it is important to start with the smallest effective dose possible, so that you can gauge your body’s reaction and adjust accordingly. Typically, people who supplement Picamilon use anywhere from 50-300 mg per day split over several administrations. Most often, people prefer to split the administrations into a morning and an evening dose. It is best to take Picamilon on an empty stomach, and depending on your preference, you can buy it in powder or encapsulated form. The effects last anywhere from 2-4 hours, but it has been shown that Kava and Valerian have the potential to increase these effects.

Phenibut Dosage

The recommended Phenibut dose is 250mg. Phenibut should only be used as needed since this supplement can be addictive. If taking phenibut regularly, some withdrawal side effects may occur upon ceasing supplementation.

How to Find the Best Price

I spent a few minutes trawling the web to find the best prices for Picamilon and Phenibut from some of the largest supplement suppliers.  Below are my findings.

Picamilon

Harvest Moon: $35.99 for 18g (150mg capsules, 120 ct)

Phenibut

Hard Rhino: $29.99 for 125g
Biovea: $31.95 for 22.5g (250mg capsules, 90 ct)

Price obviously speaks for itself, but you should also concern yourself with quality as well. You don’t want to buy something just to discover it’s full of fillers.

Picamilon and Phenibut Final Review

If you are just looking for something to help with anxiety, then either of these would work. Try both and see which is more effective. On the other hand, if you would like something to help build more endurance and muscle, then Picamilon would be a nice option.

NEWtrition 5-HTP Capsules vs. NEWtrition Melatonin Capsules

Overview:

Both 5-HTP and melatonin are known for helping in the areas of relaxation, mood, and anxiety. Anyone who is having trouble sleeping, relaxing, suffering from an inordinate amount of stress or anxiety, or even having struggles with mild depression has probably considered taking one of these supplements. NEWtrition is one of the leading providers of high quality 5-HTP and melatonin. But which product is best for each purpose? Could it be possible that these supplements may even be more effective when taken together as part of a stack?

NEWtrition 5-HTP Capsules Review:

5-HTP is an amino acid that can be found in the seeds of a woody climbing shrub native to West Africa (the Griffonia simplicifolia plant). It is also found in a number of foods like turkey, milk, potatoes, and pumpkin. It is thought to work by crossing the blood-brain barrier, where it is then converted into the neurotransmitter serotonin.supplements for relaxation

The increase in the release of serotonin is primarily responsible for most of the effects of 5-HTP. This is why the supplement is thought to be effective or at least helpful to issues as far ranging as obesity, PMS, migraines, anxiety, mild depression, and possibly even some types of addictive behavior.

NEWtrition Melatonin Capsules Review:

Melatonin is thought to be effective at restoring the natural circadian rhythms of the body. There is also evidence to suggest that it helps to regulate other hormones, including control of the timing and release of female reproductive hormones. This means that someone who works irregular hours or travels frequently and experiences jet lag could benefit from taking a melatonin supplement.

This supplement also has a number of additional common uses. It may help with anxiety, ADHD, chronic fatigue syndrome, depression, irritable bowel syndrome, headaches, and even menopausal symptoms. There is even some evidence to suggest that it can help to reduce the effect of sunburn.

Overall Impressions:

5-HTP is an amino acid and melatonin is a hormone. However, there do seem to be similar crossover effects and benefits. For example, both supplements are used for help with anxiety, ADHD, depression, fibromyalgia symptoms, and frequent headaches. On the other hand, melatonin also seems to be more effective at helping to restore normal sleep patterns.

Ultimately, the supplement that you should take depends on your particular situation. If you are simply looking to help restore normal sleep patterns, then melatonin is best. On the other hand, if you are looking for extra support to help with stress, anxiety, and even a combination of issues, you should consider using both as a stack.

Theanine and Inositol Combo for Anxiety

Everyone has experienced feelings of anxiety from time to time in their lives. For some it can be a crippling disorder that prevents us from living a happy and meaningful life, inducing panic attacks and intense bouts of worrying and fear. For others it may only be a fleeting feeling of tenseness or being on edge that won’t seem to go away no matter what you do. If you think you have tried it all I urge you to read on and discover the anxiety curbing effects that the combination of theanine and inositol can produce.

What is Theanine?worry-free supplements

Theanine is an amino acid that is commonly found in tea and to be more specific it can be found in high amounts in green tea. It is also available as an oral dietary supplement. It is commonly used as a nootropic in combination with caffeine as it produces a synergistic effect. In a number of double blind placebo controlled studies research has shown that supplementing theanine can have a direct influence on brain activity, reducing stress and relaxing the mind without causing drowsiness. In other studies, theanine benefits include improved memory and cognitive function as well as (ding ding!) reducing anxiety. To top it all off there are little to no side-effects that have been discovered from the result of supplementing theanine; even at the highest doses recorded. Therefore we can conclude the use of theanine is a viable option as a standalone anti-anxiety supplement, but we aren’t stopping there.

Inositol for Anxiety

So, what is inositol? Inositol is a chemical compound that is found in many foods; in particular fruit, especially cantaloupe and oranges. Inositol is created in your body when the phytic acid that is found naturally in foods such as seeds, nuts, legumes and whole grains interact with the bacteria in your digestive system. With its own mountain of research behind it inositol has been shown to reduce the frequency and severity of disorders that may stem from high levels of anxiety including panic attacks and mood disorders. In one double blind placebo controlled study researchers looked at subjects with lower than normal levels of inositol and administered doses accordingly, the results concluded that inositol supplementation was synonymous with lowered levels of depression and ultimately anxiety. Through the combination of these two supplements we can see the potential for a lowered overall state of anxiety.

Theanine and Inositol Dosage for Anxiety

As with all supplements it is important to find the correct dosage and to implement the supplement safely into your routine. Dosage amounts for theanine should be based on personal response but as always refer to your packaging for more information, a safe bet would to be stay under the 1000mg mark. As for inositol dosage, research has shown that 18g per day is safe but when combining with other supplements dosage should always be based off your personal response, as always refer to your products label for more information.

Sources

  1. http://www.ncbi.nlm.nih.gov/pubmed/7726322
  2. Kimura K, Ozeki M, Juneja LR, et al. l-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2006 Aug 21
  3. http://www.ncbi.nlm.nih.gov/pubmed/7416064

Green Tea for Anxiety

Green tea derives from a tea plant that is native to Asia and is called camellia sinensis. It is also the same plant that is the source of black tea. However, green tea is different not because of the plant that is used to make the tea but because it is processed in a different way compared to other teas. Green tea is also the least processed out of all of the other commercial teas and the method used helps to preserve more of the nutrients and health benefits that come with the tea. Green tea has been used for thousands of years in both Japan and China and has a good reputation for providing some great and effective health benefits including helping with anxiety by providing calming effects.

Try Green Tea for Anxiety ReliefGreen Tea Supplements for Anxiety

Green tea extract is another more concentrated form of green tea which is associated with a variety of different health benefits many of which are supported by scientific research. What is green tea extract? Essentially it is a more concentrated and nutritional form of green tea. Green tea extract acts as a powerful antioxidant that protects the body from damaging effects of free radicals. Green tea has been used for therapeutic purposes for a long time. It is made by steaming the leaves lightly and then allowing them to dry which helps to retain the properties and nutrients of the plant. Oolong tea is made by allowing the leaves to ferment slightly before drying and black tea is made by allowing the leaves to ferment for a little bit longer. Fermentation breaks down the active ingredients in the tea making the green tea or the extract.

Green tea extract is standardized in the production phase which means that it will be guaranteed that a certain percentage of the active ingredients remain present in the green tea extract capsules. Benefits of green tea extract include helping to aid in weight loss, lowering cholesterol and blood pressure, promoting oral health, helping the body fight viruses, reducing inflammation, fighting infection, promoting immune health, and slowing the aging process. Pure green tea extract is generally what you will want to look for if you want to get the maximum benefits of green tea extract.

Many people believe that green tea extract has curative effects because recent studies have indicated that the antioxidants that green tea contains help strengthen the immune system and boost health. Additionally green tea has been used for anxiety for quite some time and according to reviews has had some promising effects. Many people report that green tea extract has a calming effect on them and helps to calm their anxiety. Although green tea is not particularly known for its anti-anxiety effects it can be quite effect and especially when it is combined with L-theanine. So overall green tea is great for health but its effectiveness on anxiety is minimal at best but in some people can be a good for anxiety. However, in some cases people have actually reported that green tea increased their anxiety so you may want to watch out if that is the case for you and stop taking green tea immediately. Green tea can be purchased on drugstore.com, at Wal-Mart, vitamin shops and Amazon.

Green Tea Dosage for Anxiety

The recommended dosage of green tea extract is 350mg daily. To achieve maximum anxiety relief benefits, try adding l-theanine to green tea extract to counteract any side effects experienced from caffeine.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/18468736
  2. http://www.ncbi.nlm.nih.gov/pubmed/21303262
  3. http://www.ncbi.nlm.nih.gov/pubmed/18326618

Schisandra to Boost Mood and Relieve Anxiety

Schisandra Berries

Many times we are faced with the dilemma of taking a supplement that can enhance our mood but may bring along anxiety and other unwanted side effects. So obviously the rational decision to make is to find a supplement that does not come burdened with such adverse effects or better a supplement that relieves anxiety as well as boosts your mood. This is where the schisandra berry comes in, a natural remedy for many common ailments throughout history, anxiety among them. So, where does this mysterious fruit that is also referred to as the five flavor berry come from, and what exactly is at work here to create such an effect?mood boosters

The schisandra berry grows on the schisandra chinensis vine which is mainly found in eastern Asia. The bioactive components can be found throughout the plant but are most concentrated in the berries; therefore they are what we will focus on in this analysis of the fruit. No, nobody expects you to fly half way around the world (depending on where you are located!) to obtain the schisandra berry just as nobody expects you to import such a delicate fruit from some foreign country. Rest assured, the extract of this berry is what we are after and can be found fairly easily in most regions of the world.

Schisandra Benefits

Research surrounding schisandra is fairly conclusive in the fact that it is a powerful anti-anxiety supplement in addition to its ability to boost ones mood through lowering stress levels and enhancing performance in many facets of life. The Institute of Traditional Chinese Medicine & Natural Products concluded through animal research that regular ingestion of the schisandra extract lead to a reversal in stress-related anxiety as well as an increase in cognitive function in subjects.  The schisandra berry is a classic example of a fruit that demonstrates adaptogenic activity, which means it is completely safe, non-toxic and specifically reduces both mental and physical stress. This is the good stuff, just what we are looking for in a natural remedy to one of life’s age old problems. It doesn’t stop there though; the schisandra berry has been shown to improve coordination, concentration, and even endurance. Sometimes when we begin to break down the science behind ancient Chinese culture and herb usage we reach the point where the benefits are just be too good to be true, but they are true and there is a reason these powerful supplements have been used for thousands of years.

The focus of this analysis has been on the anti-anxiety and mood boosting effects surrounding the schisandra berry but the benefits do not stop there. While some may be so bold as to try the schisandra berry in its raw form others should opt to explore other options when it comes to supplementing the super fruit. Extract in powder form is the most common and easily accessible form and is what I recommend for any that may be interested in adding schisandra to your stack. As always pay attention to your body’s individual response and always read the packaging information on your particular supplement for more information on dosing.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/20374974

http://www.ncbi.nlm.nih.gov/pubmed/21757327

Picamilon

Picamilon
Learn how to make your own picamilon capsules

Finding a solution to manage the persistent stress and anxiety brought on by life’s ever increasing list of duties and challenges can be difficult. Some individuals who suffer under the weight of these feelings want help but don’t know where to turn.

Luckily, there is a healthy, natural approach to combating an increased sense of anxiety and high levels of stress, a supplement combination called Picamilon.

Picamilon: What is it?

Picamilon is a dietary supplement formed by the combination of Niacin and GABA.

GABA, a scientifically classified amino acid that plays the part of an essential neurotransmitter in the central nervous system, helps to decrease heightened levels of neurotransmitter activity.

Niacin, an organic compound necessary to the function of the human body, helps to protect the body’s neurons against the loss of blood flow. This compound also makes it possible for GABA to easily cross the blood-brain barrier, something it cannot normally do.

Since Picamilon easily crosses the blood-brain barrier, the user feels the effects of the supplement faster and in a much more efficient manner that with some other supplements. It also works much more effectively at increasing cerebral blood flow than either Niacin or GABA do on their own. [2]

Picamilon Benefits

Picamilon works by crossing the blood-brain barrier so that it can be broken down into its base components of Niacin and GABA. Many researchers believe that GABA deficiency plays a large role in the development of depression and panic disorders.

However, since GABA cannot cross the blood-brain barrier alone, the addition of the supplement Picamilon can solve such deficiencies.

Picamilon for Anxiety

Once this supplement hydrolyzes, the compounds promptly begin performing their different beneficial functions. The activation of the human body’s GABA receptors which provide the calming effects desired when dealing with anxiety, is one such example.

There are many positive picamillon side effects including anxiety reliefPicamilon also helps to increase blood flow to and within the brain, which subsequently provides another tranquilizing effect. This effect counteracts different physiological symptoms and is especially effective in individuals suffering from varying states of anxiety.

Unlike other methods of dealing with anxiety, Picamilon avoids the commonly associated sedative effects such as drowsiness and lethargy. [3]

The compound Niacin works to vasodilate, or to widen, the blood vessels for easier circulation which also decreases blood pressure, associated pains, and the chronic migraines many anxiety sufferers experience.

Additionally the supplement works to decrease other symptoms associated with high stress levels such as poor concentration, fatigue, restlessness, and irritability.

Other benefits of Picamilon include [1,2,3]:

  • Improves muscle strength retention and proper function
  • Promotes eye health
  • Lowers “bad cholesterol” or LDL levels
  • Can assist in improving ability to sleep

Picamilon Side Effects

Surprisingly, Picamilon has very few, if any negative effects on humans. Studies have shown that it produces no allergenic, teratogenic, embryotoxic or carcinogenic effects on subjects given the subject over those given placebo supplements. [2]

Unlike some other anxiolytic supplements, Picamilon is also shown to be less likely to present problems related to tolerance buildup, withdrawal, and addiction. [3]

Also noted in similar studies, ” The use of Picamilon in depression, along with moderate doses of tricyclic antidepressants, enabled the doses of the latter to be reduced. In patients with alcoholism, Picamilon abolished many withdrawal symptoms, especially apathy, weariness and lethargy. The patients later become more tranquil, less fussy and anxious, and their working capacity improved.” [2]

Picamilon Dosage

As mentioned above, Picamilon is considered a very safe supplement, with a low chance of increasing liver toxicity. The standard dosage range tends to fall between 50-300 mg per day, which can be split throughout the day. Picamilon tends to work best when taken on an empty stomach and its effects will usually last from 2 to 4 hours. [4]

Like with many supplement, the best way to determine your ideal dosage is to start at the smallest recommended amount and increase from there. Often this will mean taking a single capsule, usually around 150 mg, but this supplement can also be purchased in bulk powder form if you would like to customize your dosage.

Picamilon can be found online, if you decide that you would like to experience the benefits of this supplement firsthand.

Picamilon Sources

  1. http://en.wikipedia.org/wiki/Picamilon
  2. http://www.lef.org/magazine/mag97/july-lbn297.htm
  3. http://nootriment.com/picamilon-side-effects/
  4. http://nootriment.com/picamilon-dosage/